Saffron in Medicine?

Medicinal uses

Saffron has many medicinal uses:
1- A 2010 double-blind, placebo-controlled study found saffron helped mild to moderate Alzheimer’s disease.

2- Crocetin, an important carotenoid constituent of saffron, has shown significant potential as an anti-tumour agent in animal models and cell culture systems.

Saffron inhibits DMBA-induced skin carcinoma in mice when treated early.

3- Animal testing has shown that the aqueous and ethanolic extracts of saffron and its constituents, crocin and safranal, have antidepressant activities in a forced swimming test.

4- Both saffron stigma and petals are said to be helpful for depression.


5- Satiereal (Inoreal Ltd, Plerin, France), a novel extract of saffron stigma, may reduce snacking and enhance satiety through its suggested mood-improving effect, and thus contribute to weight loss.

6- Saffron was found to be effective in relieving symptoms of PMS.

7- Saffron, crocins and crocetin inhibit breast cancer cell proliferation.

8- Crocus sativus (most saffron research refers to the stigmas but often this is not made clear in research papers) inhibits histamine H1 receptors in animals, suggesting a potential use in allergic disorders. (Histamine is a biological amine that plays an important role in allergic responses.)

9- Saffron may have a protective effect on the heart.

10- 2011 double-blind, human trial found the use of 100 mg of saffron daily has temporary immunomodulatory activities.