Saffron in Medicine?
Saffron has many medicinal uses:
1- A 2010 double-blind, placebo-controlled study found saffron helped mild to moderate Alzheimer’s disease.
2- Crocetin, an important carotenoid constituent of saffron, has shown significant potential as an anti-tumor agent in animal models and cell culture systems.
Saffron inhibits DMBA-induced skin carcinoma in mice when treated early.
3- Animal testing has shown that the aqueous and ethanolic extracts of saffron and its constituents, crocin and safranal, have antidepressant activities in forced swimming test.
4- Both saffron stigma and petals are said to be helpful for depression.
5- Satiereal (Inoreal Ltd, Plerin, France), a novel extract of saffron stigma, may reduce snacking and enhance satiety through its suggested mood-improving effect, and thus contribute to weight loss.
6- Saffron was found to be effective in relieving symptoms of PMS.
7- Saffron, crocins and crocetin inhibit breast cancer cell proliferation.
8- Crocus sativus (most saffron research refers to the stigmas but often this is not made clear in research papers) inhibits histamine H1 receptors in animals, suggesting a potential use in allergic disorders. (Histamine is a biological amine that plays an important role in allergic responses.)
9- Saffron may have a protective effect on the heart.
10- A 2011 double blind, human trial found use of 100 mg of saffron daily has temporary immunomodulatory activities.